Oregano is commonly known for its culinary use — stirred into pasta sauce, sprinkled on pizza or roasted potatoes or in a salad dressing — but it also has a long history of medicinal use. The leaves of the oregano plant contain various chemical compounds, and research findings suggest they may have antibacterial, antifungal and chemopreventive properties. When consumed in excess, these same compounds can have serious side effects, even resulting in death.
Oregano Oil Benefits
Carvacrol may fight the growth of bacteria, including antibiotic-resistant bacteria, as noted in a study published in 2015 in Frontiers in Microbiology.
Thymol has antifungal effects, useful for treating oral thrush, or candidiasis, as reported in a 2015 study in BMC Complementary and Alternative Medicine.
Rosmarinic acid helps modulate tumor necrosis factor, an immune system substance that plays a role in cancer treatment and prevention, according to a 2010 study in Cancer Letters.
Oregano Oil Side Effects
Unlike the dried or fresh herb used in cooking, oregano oil for medicinal use is highly concentrated. It can be very easy to take too much without even realizing it. However, thymol in oregano oil can have toxic effects when used in large doses over a long period of time.
Potential side effects of excessive intake of thymol include:
- Stomach pain
- Cardiac and respiratory collapse
Oregano — leaf and oil — may also increase the risk of bleeding, so people with bleeding disorders should avoid it. Additionally, people who are having surgery should not use oregano for two weeks before their procedure.
Oregano may also lower blood sugar, so diabetics should be careful when consuming the leaf, but especially the oil. Finally, pregnant women are advised not to take oregano medicinally in any dose because it may increase the risk of miscarriage.
Oil of Oregano Dosage
As a supplement, oregano oil is typically sold in liquid and capsule form. It isn't regulated by the FDA, and no recommended dosage has been established. There are many different oil of oregano supplements on the market: extracts and standardized oils with varying amounts of active compounds.
Oregano oil may be 100 percent pure or mixed with other oils. Stick to the recommended dosage and check in with your doctor to make sure oregano oil won't interact with any medications you're currently taking.
- Journal of Zhejiang University Science B: Chemical Composition and Antioxidant Activities of Essential Oils From Different Parts of the Oregano
- Frontiers in Microbiology: Antimicrobial Activity of Essential Oils and Carvacrol, and Synergy of Carvacrol and Erythromycin, Against Clinical, Erythromycin-Resistant Group A Streptococci
- BMC Complementary and Alternative Medicine: Antifungal Activity and Mode of Action of Thymol and Its Synergism With Nystatin Against Candida Species Involved With Infections in the Oral Cavity: An in Vitro Study
- Cancer Letters: Rosmarinic Acid Sensitizes Cell Death Through Suppression of Tnf-α-Induced Nf-κB Activation and Ros Generation in Human Leukemia u937 Cells
- Journal of International Medical Research: Effects of Origanum Onites on Endothelial Function and Serum Biochemical Markers in Hyperlipidaemic Patients
- Phytotherapy Research: Investigation of Origanum Nites, Sideritis Congesta and Satureja Cuneifolia Essential Oils for Analgesic Activity
- Journal of Nutritional Biochemistry: Carvacrol Prevents Diet-Induced Obesity by Modulating Gene Expressions Involved in Adipogenesis and Inflammation in Mice Fed With High-Fat Diet
- Phytotherapy Research: Inhibition of Enteric Parasites by Emulsified Oil of Oregano in Vivo
- Toxnet: Thymol
- WebMD: Oregano