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Flucloxacillin for Acne

author image J.M. Andrews
J.M. Andrews has been a professional journalist for more than 20 years. She specializes in health and medical content for consumers and health professionals. Andrews' background in medicine and science has earned her credits in a wide range of online and print publications, including "Young Physicians" magazine.
Flucloxacillin for Acne
Dermatologists occasionally prescribe flucloxacillin for acne treatment.

Dermatologists commonly treat inflammatory acne with antibiotics. But some acne resists treatment with the most commonly used antibiotics, which include minocycline and erythromycin, according to the American Academy of Dermatology. If this is the case for you, your dermatologist might prescribe flucloxacillin to treat your acne.

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Inflammatory acne always includes bacterial infection, according to the Cleveland Clinic. When you develop whiteheads and blackheads, bacteria can multiply and grow in the skin oil behind those blockages, causing infection and inflammation. In some cases, the bacterial infection leads to pus-filled cystic acne and other severe forms of the skin disease.


Antibiotics such as flucloxacillin treat the bacterial infection in inflammatory acne, according to the Flucloxacillin is an antibiotic in the penicillin family, so if you're allergic to penicillin, you shouldn't take flucloxacillin. Adults and teenagers typically will take 250 to 500mg of flucloxacillin every six hours to treat acne.


If flucloxacillin works to clear your complexion, you'll typically start to see some pimples clearing within a week or two of starting the medication. Common side effects of flucloxacillin include mild diarrhea, yeast infections and headaches, according to the Rare side effects can include convulsions, severe abdominal pain and bloody diarrhea. If those occur, contact your physician immediately.


Few medical studies have looked at the effects of penicillin-type antibiotics such as flucloxacillin in acne. One study, led by Dr. W. Gubelin and published in the Spanish-language medical journal "Revisto Latinoamericana de Microbiologia" in 2006, found that strains of acne-promoting bacteria were susceptible to penicillin. On the forums at, several patients have reported that flucloxacillin helped them clear their acne.


If your doctor decides to prescribe flucloxacillin for your inflammatory acne, you may need to use a topical treatment, such as benzoyl peroxide, along with the flucloxacillin, according to Treatment with benzoyl peroxide, a proven acne-fighter, can help prevent your acne from becoming resistant to flucloxacillin.

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