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The Best Meal Replacement Powders

author image Adam Cloe Ph.D./M.D.
Adam Cloe has been published in various scientific journals, including the "Journal of Biochemistry." He is currently a pathology resident at the University of Chicago. Cloe holds a Bachelor of Arts in biochemistry from Boston University, a M.D. from the University of Chicago and a Ph.D. in pathology from the University of Chicago.
The Best Meal Replacement Powders
A bowl of protein powder. Photo Credit: Magone/iStock/Getty Images

Meal replacement powders are designed to help you add protein to your diet without forcing you to alter what you consume too much. They are intended to be mixed into a beverage, which can either be used as a substitute for a meal or as an addition to your diet. There are a variety of different meal replacement powders, each of which differs in terms of its taste, ingredients and nutritional value. If you choose to use meal replacement powders, keep in mind that this is a serious decision and you should talk with your physician before taking this step.

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Myoplex is a highly regarded meal replacement powder made by EAS, one of the top supplement manufacturers. As the review on UltimateFatBurner explains, one of the reasons why Myoplex is regarded as one of the top meal replacement powders is its superior taste. Not only does Myoplex come in a variety of flavors, including basic vanilla, strawberry and chocolate, but special packs of different chocolate and tropical flavors are also available. Although Myoplex is more expensive than many other choices with a cost of $2.02 per serving, it is regarded by many as the best meal replacement powder in terms of taste. There are other varieties of the Myoplex product line, including Myoplex Deluxe and Myoplex Lite, but some feel that these varieties do not represent an improvement over the original Myoplex. One serving of Myoplex will add 300 calories, 42 grams of protein, 25 g of carbohydrates and 2 g of fat to your diet


Isopure, made by Nature's Best, is notable for its simplicity. As the review on notes, this product has few "filler" ingredients, such as corn syrup or oils. It also has a very short ingredient list, which means that if you consume it, you will get more of the nutrients from the main ingredients, such as whey protein and a mixture of vitamins, minerals and amino acids. Although notes that Isopure is not the best-tasting or least expensive meal replacement powder available, it is not so low on either measure that it is not recommended. Each Isopure shake contains 300 calories, 50 g of protein, 25 g of carbohydrates and no fat.

Optimum Nutrition's 100% Whey MRP

Optimum Nutrition's 100% Whey MRP is the top meal replacement powder in terms of cost per serving. According to BodyBuildingForYou, one serving of this meal replacement powder costs $1.29. That's well below the $2.02 already mentioned with Myoplex, which itself is just a tad less expensive than Isopure, which comes in at $2.07 per serving. Similarly, Optimum's product also scores least expensive on another important scale, the lowest cost of meal replacement powder per gram of protein: just under three cents per gram. This solidifies Optimum's place as first in terms of value. One serving of this product contains 290 calories, 45 g of protein, 20 g of carbohydrates and 4 g of fat.

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