Though many countries have banned products containing ephedra, Xenadrine with ephedra still remains in a number of markets. It was originally introduced as a thermogenic fat-burning supplement. Its ingredients have been scrutinized amidst reports of potentially harmful side effects.
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Because it is difficult to determine how a person will react to Xenadrine with ephedra, directions recommend gradually increasing the dosage. Makers suggest taking one tablet per day for the first week and then increasing the dosage to two tablets per day once you feel comfortable doing so. Up to three tablets per day can be "safely" ingested, but no more than three in a 24-hour period. Do not take this supplement, however, without the advice of a licensed physician as safety is questionable.
Ingredients and Supplement Facts
The serving size for this product is listed as two capsules; each bottle has 60 capsules. Xenadrine RFA-1 contains 335 mg of ma huang, another name for ephedra. This translates to 20 mg of ephedra. Other active ingredients include: 85 mg of bitter orange, 40 mg of panothenic acid, 910 mg of guarana extract, 105 mg of white willow bark and 50 mg of ginger root. It also provides 225 mg of a proprietary thermo synergist blend that contains L-tyrosine, L-carnitine, fisetin, magnesium phosphate and DMAE. Based on government bans of certain ingredients, this product may differ by location.
Ephedra, originally used by the Chinese, is also known by the names epitonin, ma huang, sinica and sida cordifolia. It is a stimulant that increases heart rate and blood pressure while constricting blood vessels. The United States Food and Drug Administration has linked dietary supplements with ephedra to serious side effects and even death.
The FDA acknowledges that dietary supplements containing ephedra present an increased risk of heart problems, heart attack and stroke because they raise blood pressure and cause undue stress to the circulatory system. The agency banned the sales of these products in 2004. A consumer advisory issued by the National Center for Complementary and Alternative Medicine cites excessive calls to poison control centers from users of ephedra alkaloids as an additional factor in its decision to warn about this substance.