The adrenal glands, located on top of the kidneys, produce a corticosteroid hormone called cortisol. Cortisol regulates body systems in times of stress. Conditions, such as adrenal gland disease or a pituitary tumor, may cause a continuous amount of high levels of cortisol. High levels of cortisol in the blood causes a medical condition called Cushing's syndrome. Correcting the cause of the increased cortisol ends the symptoms associated with the condition and cures Cushing's syndrome, most of the time, according to Medline Plus.
Weight Gain
With Cushing's syndrome, weight gain usually occurs in the upper body. The gain may lead to obesity, even in individuals with previous normal body weight. The fat stays around the body, face and neck. The arms and legs remain normal size.
Fragile Skin
The skin becomes thin and fragile with too much cortisol. The skin may tear and bruise easily. Once damaged, the skin has difficulty healing. This may occur with cuts or insect bites also, according to the Mayo Clinic. Stretch marks may appear on the body from the combination of frail skin and increased weight gain.
Moon Face
The shape of the face takes on a round shape with Cushing's syndrome. This is often referred to as a moon face.
Muscle and Bone Weakness
Muscular weakness can occur in individuals with sustained high levels of cortisol. The weakness in the bones may be severe enough to lead to fractures, even with everyday activities, states the National Endocrine and Metabolic Diseases Information Service.
Buffalo Hump
A fatty lump of tissue may develop on the back, up between the shoulders. This lump is sometimes referred to as a buffalo hump.
Irregular Menstrual Cycle
Women with Cushing's syndrome may also experience changes in their menstrual period. It may become irregular in length or stop completely.
Excessive Hair Growth
Women are especially bothered with the excessive hair growth associated with Cushing's syndrome. The increased amount of hair can grow on the face, neck and chest.
Decreased Libido
Men may experience with a decreased libido associated with the high levels of cortisol. The decrease in sex drive may also be coupled with an inability to sustain an erection, causing erectile dysfunction.
Increased Thirst and Urination
An increased desire to drink fluids may occur with Cushing's syndrome. The increased fluid intake also signals an increased need to urinate frequently.
Emotional Distress
Increased cortisol levels may cause an inability to control emotional responses. Depression, increased irritability and feelings of anxiousness may occur as a result.
