Acacia rigidula or "blackbrush" is a perennial shrub and member of the legume family. Native to southern Texas and central Mexico, it has been used by Native Americans for decades. Burgeoning obesity rates in North America and the anorectic effects of Acacia rigidula on weight loss spurred interest in the herb as a remedy for overweight/obesity.
About 40 chemical compounds and amines comprise Acacia rigidula. These include compounds include amphetamines, dopamines, hordenine, mescaline, tyramines, tryptamines, nicotines and amides. Acting on the pituitary adrenal axis they induce the release epinephrine/adrenaline, norepinephrine/noradrenaline, dopamine and catecholamines that stimulate beta-receptors to increase fat breakdown and metabolic rate and suppress appetite.
Increases Weight Loss Through Lipolysis
Acacia rigidula suppresses appetite. You eat less. The shortage of carbohydrates for fuel due to appetite suppression induces the body to use fats for energy. N-methyl-phenylethylamine, methylsynephrine, and theobromine in Acacia rigidula promote fat breakdown and subsequent weight loss.
Beta-adrenergic systems control lipolysis, or fat breakdown, during stressful periods and intense physical activity. The alpha-adrenergic system is in control during periods of rest.
Enhances Metabolic Rate
Acacia rigidula speeds up metabolism. The activation of beta-adrenergic receptors through Acacia rigidula induces the release of epinephrine, norepinephrine and catecholamines that increase metabolic rate by dilating peripheral blood vessels, increasing pulse rate and heart rate.
Phenylethylamine hydrochloride (PEA) increases metabolic rate.
Acacia rigidula stimulates norepinephrine that reduces appetite, increases energy and promotes fat loss. The methylsyneprine in Acacia rigidula also stimulates lipolysis and increases resting metabolic rate.
Amphetamines decrease appetite by inhibiting the action of neuropeptide Y, an appetite neurotransmitter abundant in the brain. Amphetamines are central nervous system stimulants. They increase blood pressure, heart rate, metabolic rate, and serum concentration of free fatty acids through the action of catecholamines, the "fight or flight" hormones.
Enhances Good Mood
Phenylethylamine hydrochloride in Acacia rigidula stimulates the central nervous system to enhance mood and promote a sense of well-being and satiety. The herb is believed to trigger the release of dopamine in the pleasure-sensing area of the brain. Mescaline, a non-selective serotonin receptor agonist present in small amounts in the herb elicits a "dream-like" feeling in negligible amounts.
Increases Body Temperature
Beta3-adrenergic compounds the herb boosts body temperature due to greater tissue oxygen consumption. Tryptamine is a neurotransmitter responsible for thermogenesis - the generation of body heat that plays a role in weight loss.
There are numerous herbal weight loss formulations with Acacia rigidula in varying potencies and forms on the market. However, before taking the supplement, see your doctor. Herbal preparations may interfere with medication causing serious health risks. Many herbal weight loss formulations are not approved by the FDA, and there are scant human studies proving the supplements' safety and efficacy. Use Acacia rigidula for weight loss with medical supervision.
- PubMed: Beta(3)-adrenoceptor agonist-induced increases in lipolysis, metabolic rate, facial flushing, and reflex tachycardia in anesthesized rhesus monkeys
- The Journal of Lipid Research: Norepinephrine-induced lipolysis in rat fat cells from visceral and subcutaneous sites:role of hormone-sensitive lipase and lipid droplets
- PubMed: Learning new tricks from old dogs: beta-adrenergic receptors teach new lessons on firing up adipose tissue metabolism