Arthritis is the inflammation of joints defined by pain, swelling and stiffness in the joints and fatigue. There are more than 100 types of arthritis including rheumatoid arthritis, osteoarthritis, juvenile arthritis and gout. About 50 million adults in the United States suffer from some form of the disease, according to 2010 information from the Centers for Disease Control and Prevention. Treatment generally involves medications, surgery, exercise and diet. Certain supplements such as vitamin B-6 may also help manage the condition.
About Vitamin B-6
Vitamin B-6 is part of the water-soluble vitamin B complex that plays an important role in the metabolism of carbohydrates and fats, as well as in the generation of energy. It also helps the body make neurotransmitters and promotes proper functioning of the immune system. Daily recommendations for vitamin B-6 range from 0.1 to 2 mg. Food sources of B-6 include chicken, turkey, salmon, dairy products, lentils, beans and whole grains. Some studies suggest that B-6 can help treat depression, morning sickness, heart disease, arthritis and premenstrual syndrome, but more research is needed, notes the University of Maryland Medical Center. Consult a doctor to determine a dose that is right for you.
Link Between Vitamin B-6 and Arthritis
In a study published in the September 2010 issue of the "European Journal of Clinical Nutrition," large doses of vitamin B-6 supplements of 100 mg per day inhibited the production of chemicals that cause inflammation in rheumatoid arthritis patients. Another study published in the January 2010 issue of "The Journal of Nutrition" also indicates that increased intake of vitamin B-6 can help provide protection against inflammation. In fact, abnormal vitamin B-6 levels may increase the severity of symptoms in rheumatoid arthritis patients, according to an article published in "The American Journal of Medicine" in March 2003.
Side Effects
High doses of vitamin B-6 supplements can lead to neurological disorders such as loss of sensation in legs and imbalance, notes the UMMC. Other adverse reactions such as nausea, abdominal pain, loss of appetite and increased sensitivity to light may also occur. Allergic reactions have been reported in rare cases. Vitamin B-6 supplements also interfere with certain antibiotics, antidepressants and chemotherapeutic agents.
Precautions
Always consult a doctor before using vitamin B-6 supplements to avoid possible complications. Inform your doctor about any other medications you might be taking and pre-existing conditions you may have as B-6 supplementation may cause adverse reactions.
References
- Centers for Disease Control and Prevention; Arthritis; October 20, 2010
- "European Journal of Clinical Nutrition"; Vitamin B6 Supplementation Improves Pro-Inflammatory Responses in Patients with Rheumatoid Arthritis; S-C Huang, et al.; September 2010
- "The Journal of Nutrition"; Vitamin B-6 Intake Is Inversely Related to, and the Requirement Is Affected by, Inflammation Status; Martha Savaria Morris, et al.; January 2010
- "The American Journal of Medicine"; Abnormal Vitamin B6 Status is Associated with Severity of Symptoms in Patients with Rheumatoid Arthritis; En-Pei I Chiang, et al.; March 2003
- University of Maryland Medical Center; Vitamin B6 (Pyridoxine); Steven D. Ehrlich, NMD; June 18, 2009
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