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The Dosage of Magnesium for Anxiety

author image Kelli Cooper
Kelli Cooper has been a writer since 2009, specializing in health and fitness. She holds a Bachelor of Arts in political science from Rutgers University and is a certified personal trainer with the American Council on Exercise.
The Dosage of Magnesium for Anxiety
Magnesium supplements for the treatment of anxiety do not have strong scientific backing. Photo Credit Medioimages/Photodisc/Photodisc/Getty Images

The mineral magnesium plays several important roles in the body. Low levels can lead to a number of symptoms and according to the University of Maryland Medical Center, anxiety ranks among them. This suggests supplementing with magnesium might alleviate anxiety, but according to the University of Michigan Health System, the evidence for this therapeutic benefit is weak. Some dosage guidelines exist but consult with your doctor for guidance on whether or not magnesium supplementation is appropriate and at what dose.


Austrian researchers wanted to conduct an experiment to test the idea that magnesium deficiency influences mood. The study, published in the December 2004 issue of “Neuropharmacology,” examined the effects of a magnesium-deficient diet on the behavior of mice. They observed this change in diet led to an increase in anxiety-and-depression-related behavior.

A study published in the January 2009 issue of the “Australian and New Zealand Journal of Psychiatry” found a strong correlation between magnesium intake and levels of depression in community-dwelling adults. The link between magnesium and anxiety was “weaker and not statistically significant.” Whether or not magnesium will actually help reduce your anxiety is not clear but being a generally safe supplement, it cannot hurt to try.

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Suggested Dosage

The University of Michigan Health Center notes magnesium supplementation might help with mild anxiety. It notes a typical dose of 200 mg to 300 mg three times a day.

Caution in Certain Individuals

If you have heart disease or kidney disease, do not take magnesium supplements without consulting with your doctor first. If you are pregnant or nursing, your magnesium intake should not exceed 350 mg, which is the safe upper limit in this instance, according to the Beth Israel Deaconess Medical Center. Because the recommended dosage for treating anxiety far exceeds this, magnesium supplementation for anxiety appears an inappropriate option.

Other Considerations for Use

Make sure to get enough B-6 either through diet or supplementation as inadequate levels will decrease magnesium absorption. Magnesium might inhibit absorption of several classes of antibiotics -- take these supplements one hour before or two hours after the medications. Supplementing with larger amounts of magnesium can create a calcium deficiency if you already have insufficient levels. Consider getting your calcium levels checked before using magnesium supplements.

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