Multiple sclerosis is an autoimmune disorder that occurs when the immune system attacks the protective covering of the nerve cells, also known as the myelin sheath. This, in turn, affects the brain and spinal cord and slows or completely stops the conduction of nerve impulses. Symptoms vary depending on the nerves impacted but generally include loss of balance and coordination, muscle spasms, loss of sensation, poor bladder control and dizziness. There is no cure for multiple sclerosis, although some medications and supplements such as curcumin may help manage the symptoms.
Curcumin
Curcumin is the biologically active, polyphenolic component of turmeric, a characteristic yellow powder extracted from the roots and underground stems of the Curcumin longa plant. Curcumin, or turmeric, supplements possess immense medicinal value and have been used to manage a variety of conditions, including diabetes, arthritis, infections, ulcers and certain types of cancers. Curcumin is available as capsules, tinctures and fluid extracts. Its dose may vary in different people. Consult your doctor to determine the dose and form that is right for you, based on your age and overall health.
Multiple Sclerosis
Curcumin possesses significant anti-inflammatory and neuroprotective activity and may thereby play an important role in the treatment of multiple sclerosis, according to a study published in the March 2011 issue of the journal "International Immunopharmacology." Another study published in a 2007 issue of the journal "Advances in Experimental Medicine and Biology" states that curcumin can reduce the symptoms of autoimmune diseases, including multiple sclerosis, by regulating the release of inflammatory chemicals in the immune system. However, more studies are needed to establish the effective dose, safe regimen and mechanism of action of curcumin for autoimmune diseases, the author says. Some animal studies also indicate that curcumin may slow the progression of multiple sclerosis by inhibiting the secretion of interleukin-12, a chemical that signals the immune cells to damage myelin sheath, says Dr. Kewal K. Jain, author of the book "The Handbook of Neuroprotection."
Side Effects
Curcumin is generally safe to use, although an overdose of the supplement may cause upset stomach and ulcers. Curcumin supplements may also interfere with diabetes medications and excessively lower the blood sugar levels. They may also alter the action of blood-thinning and antacid medications.
Precautions
You may find curcumin supplements at natural food stores. However, consult your doctor before using them. The Food and Drug Administration does not regulate curcumin or turmeric products in the United States. Make sure that the product you intend to use has been tested for its safety and efficacy. Your pharmacist may be able to guide you in this regard.
References
- "International Immunopharmacology"; Curcumin has Bright Prospects for the Treatment of Multiple Sclerosis; Lin Xie, et al.; March 2011
- "Advances in Experimental Medicine and Biology"; Curcumin and Autoimmune Disease; J.J. Bright; 2007
- "The Handbook of Neuroprotection"; Kewal K. Jain; 2011
- University of Maryland Medical Center: Turmeric
