Carboplatin is a chemotherapy medication given to cancer patients typically through intravenous infusion. According to the MayoClinic.com carboplatin treats several types of cancer including bladder, breast, lung, testicular, brain, skin, ovarian and endometrial. Chemotherapy is designed to kill cancer cells but unfortunately kills the body's normal cells also which causes side effects.
Nausea and Vomiting
Nausea and vomiting occurs due to effected receptors in the brain and damage of the stomach lining. The Chemotherapy Source Book states that nausea and vomiting are common side effects of carboplatin. Nausea typically occurs 24 hours after infusion but also less commonly occurs several days after chemotherapy.
Hair Loss
Rapidly growing hair follicles are killed by administration of carboplatin. Hair loss typically occurs two to three weeks after the first infusion. Hair loss patterns differ and consist of slow or sudden and total loss. Hair regrows several weeks after chemotherapy is discontinued.
Low Platelets
Damage to platelets by carboplatin occurs because they too are rapidly growing cells. Low platelet counts increase the risk for bruising and bleeding in cancer patients. According to The Chemotherapy Source Book platelet counts are at their lowest 21 days after infusion.
Anemia
Anemia occurs due to the death of red blood cells. Anemia commonly causes fatigue and weakness in cancer patients. Chemocare.com states that counts reach their lowest point 10 to 14 days after chemotherapy. Anemia also causes low blood pressures, shortness of breath and dizziness.
Risk for Infection
Cancer patients receiving carboplatin present a higher risk for acquiring infections because the white blood cells of the immune system have become damaged. Low white blood cell counts make patients more susceptible to infection and make it more difficult for the body to fight infection.
Fertility Complications
The Chemotherapy Source Book also states that fertility problems often occur with the use of carboplatin. Complications can include lack of menstruation and ovulation, impotence and sterility.
Less Common Side Effects
In addition to common side effects Chemocare.com and The Chemotherapy Source Book list several other less common side effects. These include allergic reactions, numbness of feet and hands, diarrhea, mouth sores, kidney damage and abnormal blood tests.
References
- Chemocare.com: Carboplatin
- "The Chemotherapy Source Book"; Michael C. Perry, PhD.; 2007
- MayoClinic.com: Carboplatin Drug Information
- MayoClinic.com: Carboplatin Drug Information



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