People who suffer from frequent allergy symptoms such as nasal congestion or sneezing may find relief through the use of diphenhydramine hydrochloride. This over-the-counter antihistamine medication works by limiting the action of an allergy-inducing substance called histamine. Before taking this medication, people should be aware of potential diphenhydramine hydrochloride side effects.
Drowsiness or Excitability
Severe drowsiness can occur as a side effect of diphenhydramine hydrochloride in certain people, according to RxList. Increased drowsiness can occur shortly after taking this antihistamine and can affect a person's ability to remain alert and focused while driving or participating in potentially hazardous activities. Alternatively, certain people—particularly children—can become unusually excited or nervous after treatment with diphenhydramine hydrochloride, explain health experts with MedlinePlus. Affected people can appear fidgety or restless and can have difficulty falling asleep or staying asleep through the night. These side effects of diphenhydramine hydrochloride are temporary but can recur with subsequent dosing.
Dry Nose, Throat or Mouth
After taking a dose of diphenhydramine hydrochloride, people can experience sensations of dryness within the nose, throat or mouth, according to Pfizer, a pharmaceutical manufacturer of this medication. Increased nasal or oral dryness can be uncomfortable and can contribute to a sore throat or increased nasal congestion and thirst.
Upset Stomach
Upset stomach can develop after a person takes this antihistamine. Affected people can experience nausea, vomiting or a decrease in appetite, explains MedlinePlus. Certain people can also develop constipation, which can contribute to abdominal pain, cramping or bloating. Eating a small snack can help limit the development of upset stomach side effects in people taking diphenhydramine hydrochloride.
Chest Congestion
People taking diphenhydramine hydrochloride can develop an increase in chest congestion as a side effect of treatment, explain health professionals with Drugs.com. A person's chest mucus can also thicken, contributing to breathing difficulties, wheezing or chest tightness. These side effects of diphenhydramine hydrochloride are temporary and typically subside with continued use.
Headache or Weakness
Treatment with diphenhydramine hydrochloride can cause side effects of headache or weakness in certain people, explain professionals with Pfizer. Painful headache side effects are typically mild, but may disrupt a person's ability to remain focused or attentive while at work or school. Sensations of weakness can contribute to increased fatigue or drowsiness in certain people. Affected people can experience difficulty moving about or lifting things as normal. These side effects generally resolve with continued use of diphenhydramine hydrochloride.
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