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How to Use Celebrex & Ibuprofen

by
author image Sharon Takiguchi
Individual expertise lies in the healthcare discipline with over 40 year's front line experience. The attached resume demonstrates in depth expertise in medical/health practice, teaching, research, law and publication. The work settings ranged from private/public hospitals and clinics, insurance companies, private/public colleges to military healthcare settings. Illness prevented publication over the last year, but health status stabilized.
How to Use Celebrex & Ibuprofen
Celebrex and ibuprofen treat health conditions as long as the individual remains on the drug. Photo Credit tablets image by sanyal from <a href='http://www.fotolia.com'>Fotolia.com</a>

The National Institute of Arthritis, Musculoskeletal and Skin Diseases describes Celebrex and ibuprofen as belonging to the category of medications called nonsteriodal anti-inflammatory drugs (NSAIDs). The NSAID drugs relieve pain, reduce inflammation and lower elevated body temperatures. Celebrex and ibuprofen work well when taken with food. The NSAIDs have no effect on curing diseases, but exert their effect by controlling the symptoms of diseases while the person stays on the medications.

Step 1

How to Use Celebrex & Ibuprofen
NSAIDs exert their effect on the COX-1 and COX-2 enzyme systems. Photo Credit molecules of the chemical formula image by Oleg Verbitsky from <a href='http://www.fotolia.com'>Fotolia.com</a>

Identify the underlying mechanisms of Celebrex or ibuprofen. According to "Goodman & Gilman's The Pharmacological Basis of Therapeutics," these NSAIDs exert their actions on the enzyme systems cyclooxygenase -1 or COX-1 and cyclooxygenase -2 or COX-2. Ibuprofen inhibits both COX-1 and COX-2; whereas Celebrex impedes only COX-2.

Step 2

How to Use Celebrex & Ibuprofen
Individuals with osteoarthritis in joints like the hand benefit from Celebrex or ibuprofen. Photo Credit hand and mud image by Alfonso d'Agostino from <a href='http://www.fotolia.com'>Fotolia.com</a>

Determine if a condition exists that would benefit from the actions of Celebrex or ibuprofen. "Davis's Drug Guide for Nurses" indicates that both drugs produce effective treatment of pain and inflammation in osteoarthritis, rheumatoid arthritis, irritable bowel disease and ankylosing spondylitis. Celebrex also helps in the management of colorectal polyps and menstrual cramps.

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Step 3

Verify if the individual requiring the drug has any health history of stomach problems. COX-1 inhibition produces gastrointestinal or stomach bleeding in some individuals. Since ibuprofen exerts an effect on COX-1, individuals with gastric bleeding must not take ibuprofen

Step 4

How to Use Celebrex & Ibuprofen
Ibuprofen comes in a variety of dosages. Photo Credit tablets and pills image by Wilson Wong from <a href='http://www.fotolia.com'>Fotolia.com</a>

Take ibuprofen two to three times a day in oral doses of 200 to 800 mg to treat arthritic and other conditions. According to "Goodman & Gilman's The Pharmacological Basis of Therapeutics," the over-the-counter ibuprofen tablet works on the enzymes called COX-1 that causes stomach ulceration and COX-2 inhibitors that blocks the substance, prostaglandin, the chemical produced by the body that causes pain and inflammation.

Step 5

How to Use Celebrex & Ibuprofen
Celebrex dosage varies from 100 to 400 mg. Photo Credit desaturated pills image by Rachel Carter from <a href='http://www.fotolia.com'>Fotolia.com</a>

Take Celebrex one to two times a day in oral doses of 100 to 400 mg to treat arthritic and other conditions. Celebrex requires a prescription from a health care provider. The Mayo Clinic reports that the oral Celebrex capsule works only on COX-2 inhibitors to block the chemicals producing pain and inflammation in disease conditions.

Step 6

Watch for any side effects of the ibuprofen or Celebrex drugs. Common side effects of ibuprofen include gastrointestinal ulcers or bleeding; whereas, Celebrex produces allergic reactions, heart attack and stroke in some individuals. If side effects occur, the individual needs to seek emergency medical care.

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