Coumadin Long-Term Side Effects

Coumadin Long-Term Side Effects
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Coumadin, or warfarin, is an anticoagulant blood. Also called an antiplatelet medication or blood thinner, Coumadin has been used since 1941. The Cleveland Clinic notes that anticoagulant medicines prevent clots from forming in the arteries, veins and heart. Like all medications, Coumadin has potential side effects but Coumadin must be used cautiously when taken for long periods of time.

Significance

Coumadin is used to help avoid blood clots and thins the blood but has the potential for excess bleeding. Severe bleeding can be dangerous and life-threatening. PubMed Health notes that severe bleeding is most likely during initial treatment and for people older than the age of 65. Taking Coumadin for a long period of time increases the likelihood of excessive bleeding.

Function

Coumadin works by blocking vitamin K, an important component in the production of blood clotting mechanisms in the body. The U.S. Food and Drug Administration explains that Coumadin should be taken at the same time every day. It is important to regularly monitor blood levels when a person takes Coumadin to ensure that adequate amounts are being maintained.

Types

Bleeding is the most common side effect of Coumadin. Other common side effects include upset stomach, gas and bloating and an altered sense of taste. Drugs.com states that a person should report any symptoms involving bleeding issues to their doctor immediately. Signs of bleeding problems include bruising easy, pale skin, blood in stool or vomit, shortness of breath, dark urine and feeling light-headed or weak.

Considerations

The effects of anticoagulant medications such as Coumadin may last for two to five days after a person stops taking the drug. PubMed Health notes that a person should continue to take Coumadin unless instructed not to by their doctor. It is important to verify and follow instructions in gradually increasing or decreasing the amount of Coumadin dose.

Warning

Vitamin K counteracts the effects of Coumadin, according to the National Institute of Health Drug Interaction Task Force. People who take Coumadin should avoid vitamin K supplements and limit the amount of green, leafy vegetables and other foods that contain large amounts of vitamin K.

References

Article reviewed by Libby Swope Wiersema Last updated on: Mar 28, 2011

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