Evidence continues to build suggesting that deficiency in omega-3 is linked to the development of many mental health problems. Depression, bipolar disorder and even ADHD have been linked to omega-3 deficiencies. Although some preliminary trials suggest a similar relationship between omega-3 and anxiety, possible therapeutic benefits remain unclear.
Anxiety and Anxiety Disorders
To understand what is known about omega-3 and anxiety, it is important to distinguish between normal anxiety and anxiety disorders. Normal anxiety is vital to our survival. It is an early warning system for threat. Disorders develop out of this healthy system when anxiety arises without a real threat, or when the system stays constantly activated. The distinction is important as clinical trials on omega-3 and anxiety give little support for its use in treating anxiety disorders, but some support exists for its effect on normal anxiety.
Anxiety Disorders
An example of the research on omega-3 and anxiety disorders is that of clinical trials with Obsessive-Compulsive Disorder, or OCD. One trial revealed no significant reduction in symptoms of OCD with increase omega-3 intake. Dr. Brian Ross of the "Northern Ontario School of Medicine" notes, however, a second trial that provided significant preliminary results in support of omega-3's effectiveness at reducing symptoms of OCD when combined with prescription medications. If research continues to provide support, omega-3 may play a role as an adjunct to anti-anxiety medication in the future. As Ross says, "The available evidence is strong enough to justify continued study."
Research on Normal Anxiety
A sudden release of adrenaline creates the experience of heightened mental alertness and physical tension associated with normal anxiety. Clinical trials on omega-3 and normal anxiety often focus on its effect on adrenaline. An example is provided by a trial that examined student writing performance during an examination. This research showed a reduction in adrenaline of students who increased their intake of omega-3 as compared to those who took a placebo. A similar effect was found in those with social phobia -- but without a marked decrease in phobic symptoms. These results might indicate that omega-3 is effective at reducing adrenaline but has little effect on altering cognitive components that accompany anxiety disorders.
Considerations
According to the "British Journal of Nutrition," it is important to note that results supporting the effects of omega-3 on anxiety are based on small studies that often give mixed results. Even impressive results of omega-3's effects on depression are frequently from trials that use it in addition to medication. In general, omega-3 may be most effective at helping people who experience mild-to-moderate anxiety and less effective with formally diagnosed anxiety disorders.
References
- British Journal of Nutrition; "n-3 Fatty acids and mood: the devil is in the detail"; Alex Richardson; October, 2007
- Lipids in Health and Disease; "Omega-3 fatty acids as treatments for mental illness: which
- "Journal of Psychiatry and Neuroscience"; Fish Oil for Depression?; Simon N. Young; January 2008



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