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Dosage of DGL Licorice

author image Rae Uddin
Rae Uddin has worked as a freelance writer and editor since 2004. She specializes in scientific journalism and medical and technical writing. Her work has appeared in various online publications. Uddin earned her Master of Science in integrated biomedical sciences with an emphasis in molecular and cellular biochemistry from the University of Kentucky College of Medicine.
Dosage of DGL Licorice
Glycyrrhiza is an active ingredient in licorice root, and can cause serious side effects. Photo Credit TongRo Images/TongRo Images/Getty Images

Glycyrrhiza is the active ingredient in licorice, a type of herb used in medicinal remedies and food. Unfortunately, glycyrrhiza can cause serious side effects, including hormonal problems, heart attack and pregnancy complications. To prevent such side effects, licorice manufacturers have removed glycyrrhizin from this herbal treatment to produce a substance called deglycyrrhizinated or DGL licorice. Although researchers need to perform additional clinical trials in humans, DGL licorice might help relieve symptoms associated with upper respiratory infection, eczema, peptic ulcers and canker sores.

Supplement Warning

A variety of factors can determine how much DGL licorice you should take, such as your weight, age and health status. The only person who can tell you how much DGL licorice is appropriate to treat your health condition is a medical professional familiar with your medical history. Seek dosage guidance from your doctor before taking DGL licorice.

For Ulcers

Treatment with DGL licorice might help reduce stomach discomfort associated with peptic ulcers. The recommended dosage of DGL licorice for people with stomach ulcers is to chew between 200 and 300 milligrams up to three times daily, according to the University of Michigan Health System. Depending on the severity of your condition, your doctor might recommend chewing from 300 to 400 milligrams of DGL licorice extract three times daily. Alternatively, you can take 0.4 to 1.6 grams of DGL licorice extract three times each day. Usually, DGL licorice should be taken approximately 20 minutes before a meal and at bedtime.

For Canker Sores

If you suffer from painful canker sores, you might find relief following treatment with DGL licorice. To treat canker sores, wash your mouth for three minutes with a mixture of 200 milligrams of DGL licorice powder and 200 milliliters of warm water. After washing, spit the mixture into the sink. You can perform this oral rinse up to four times each day.


Despite its potential health benefits, treatment with DGL licorice isn't advised for everyone. Avoid taking this supplement if you're pregnant or breast-feeding. In addition, don't take DGL licorice if you have a history of diabetes, high blood pressure, heart failure, fluid retention, or liver, kidney or heart disease Always talk to your doctor before taking any new supplement.

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