Weight Gain or Weight Loss With Cymbalta

Weight Gain or Weight Loss With Cymbalta
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Cymbalta is the name-brand version of the drug duloxetine, which is used to treat generalized anxiety disorder and depression, as well as to treat pain and tingling associated with certain diseases and conditions. Cymbalta may spur a variety of side effects, including weight loss or weight gain. To understand Cymbalta's effects, it helps to examine how the drug affects your body.

Background

Cymbalta is classified as a selective serotonin and norepinephrine reuptake inhibitor, or SNRI. The medication works by increasing the amount of serotonin -- or the "happiness hormone" -- in the brain, helping improve mood and reduce anxiety and depression. Cymbalta also releases norepinephrine, which stops the movement of pain signals in the brain, helping to reduce sensations of pain in the body. Cymbalta is used to treat pain caused by diabetic neuropathy, fibromyalgia, and ongoing bone or muscle pain such as lower back pain or osteoarthritis.

Weight Loss With Cymbalta

A common side effect of Cymbalta is loss of appetite and weight loss, according to the Mayo Clinic. In addition to causing loss of appetite, taking Cymbalta may spur diarrhea and nausea, which can make patients eat less, therefore losing weight. According to eMedTV, clinical studies of Cymbalta have shown that up to 9 percent of people taking the medication reported a loss of appetite, and up to 2 percent of people reported weight loss. People lost about 1 to 3 lbs. while taking Cymbalta on average, according to eMedTV.

Weight Gain With Cymbalta

Weight gain is a less common side effect of taking Cymbalta. In studies conducted on Cymbalta, weight gain was reported by about 1 percent of people taking the medicine, according to eMedTV. If you experience weight gain while taking Cymbalta, see your doctor to determine if you have another medical condition causing the weight gain, or if you should switch to a different medication. Eating a low-calorie, nutritious diet can help counteract weight gain, but if the weight gain continues, consult your doctor.

Considerations

Although many people would not mind losing a few pounds from Cymbalta, if you continue to lose weight, see your doctor. Side effects such as nausea and diarrhea often go away after the first few weeks of treatment, which can stop the weight loss. If you continue to lose weight, however, you should get an exam to make sure you do not have another health condition, or your doctor may want to change your medication.

References

Article reviewed by Christine Brncik Last updated on: Jun 20, 2011

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