Advantix (permethrin) is a topical insecticide used to prevent and treat skin infestations of ticks and fleas in dogs. This treatment is applied once a month to skin at the back of a dog's neck. Advantix should not be used in cats, as this medication can cause life-threatening symptoms to develop in cats exposed to permethrin. Speak with your veterinarian if you're concerned about potential Advantix side effects.
Skin Irritation
After applying Advantix to your dog's skin, he may develop a minor skin reaction to this medication. If this occurs, you may notice that his skin appears red, irritated or dry at the site of application. Your dog may also begin to scratch more than usual due to itchy skin symptoms that occur as a side effect. Such side effects typically resolve within two to three days, say health professionals at the National Pesticide Information Center.
Hair Loss
Treatment with Advantix can cause your dog to experience hair loss or discoloration at the site of application. Your dog may develop a small, temporary bald spot on her skin where this treatment is applied. Such side effects are not permanent and resolve within a few weeks following treatment with Advantix.
Lethargy
After your dog gets treatment with Advantix, he can appear lethargic or abnormally tired. He may not appear as playful as usual or may be uninterested in his usual activities, such as running or fetching his ball. Side effects of lethargy due to Advantix are typically mild and subside within a few hours following application.
Drooling
You may notice that your dog begins to drool more than usual after being treated with Advantix. The National Pesticide Information Center reports that such side effects may be caused by your dog licking at the site of Advantix application. This can cause the medication to get into your dog's mouth, stimulating excessive drooling or lip-smacking. These side effects may be caused by the bitter taste of this medication or by a numb or tingling sensation within your dog's mouth.
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