Benadryl, generic name diphenhydramine, is an over-the-counter antihistamine for adults and children. Available as pill, liquid or topical solution, it generally treats allergies and coughs, with a common side effect of sleepiness. It is not safe for those who suffer from glaucoma, stomach ulcer, enlarged prostate, hyperthyroidism, hypertension or asthma. People should consult their doctors before taking Benadryl. Dangerous side effects are rare but can occur.
Respiratory Problems
As noted in an August 2007 "New York Times" article, dangerous respiratory side effects of Benadryl are most notable in children, whose little bodies are vulnerable to overdose. Benadryl slows the breath and sedates the child. If the child falls asleep with a pillow against his face, his natural reflex to shift may be blunted by the drug. A Montana daycare provider was convicted of homicide in 2005, according to the article, for administering Benadryl to a 1-year-old in order to get him to nap.
Next-day Sedation
Benadryl leads to next day sedation, which could compromise an ability to operate motor vehicles. A 1993 study published in "Aviation, Space, and Environmental Medicine" reports that symptoms such as tension, fatigue, inertia, confusion and excess sleepiness may be seen as long as seven hours after waking.
Unconsciousness
In May 2010, the U.S. Food and Drug Administration issued a warning about dangerous side effects of Benadryl in its topical gel form. While the drug is safe when used topically as directed, ingesting it can easily result in overdose. Symptoms include unconsciousness, hallucinations and confusion. Consumers should read the label carefully to determine whether they have the topical gel or the liquid form of the medication.
Excessive Sedation
Breast-feeding mothers who take Benadryl should monitor their infants carefully for signs of excessive sedation, which could be dangerous. According to the lactation site Kellymom.com, Benadryl is generally regarded as safe for these mothers, but because infants are so small they can be particularly vulnerable to side effects. Non-sedating antihistamines are preferred. Mothers should also monitor their milk supply closely and stop taking the drug immediately if they notice a decrease.
References
- "New York Times": These Drugs Are for Colds, Not Fidgets
- U.S. Food & Drug Administration: Medication Errors from Swallowing Topical Benadryl Extra Strength Itch Stopping Gel
- PubMed/"Aviation, Space, Environmental Medicine"; The Effects of Benadryl and Hismanal on Mood, Physiological Measures, Antihistamine Detection and Subjective Symptoms; V.J. Rice, H.L. Snyder; August 1993
- Drugs.com: Benadryl
- Kellymom.com: Cold and Allergy Remedies Compatible with Breastfeeding



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