Lipoflavonoid is an over-the-counter (OTC) supplement marketed for Meniere's disease with its symptoms of feeling ear fullness, dizziness, nausea and "ringing in the ears" called tinnitus. It is made up of vitamins B-1, 2, 3, 6 and 12 and other components found in B-complex vitamin supplements with the addition of 300 mg of lemon bioflavonoid complex, the active ingredient. The therapeutic effects of multivitamins like Lipoflavonoid is unproven, while possible allergic and other side effects are possible, according to the Mayo Clinic.
Serious Side Effects
Serious side effects of Lipoflavonoid use include hives; breathing problems; and swelling of your facial areas like the lips, tongue or throat. Such allergic reactions may need immediate medical attention, according to Revolution Health.
Nausea and Headaches
Less serious reactions to Lipoflavonoid use includes an odd taste in your mouth and nausea. Revolution Health also states that you may suffer headaches form using the supplement.
Itching and Rashes
Using Lipoflavonoid or other B-complex supplements can result in itching and rashes, according to the Mayo Clinic. The supplement has been linked with rosacea fulminans, a dermatological disorder that looks like severe acne.
Optic Nerve Damage
Lipoflavonoid and other B complex supplements should not be used in conjunction with Leber's disease, a hereditary optic nerve atrophy. According to the Mayo Clinic, the supplement can cause severe harm to the optic nerve during the onset of Leber's disease.
Black or Bloody Stools
Bowel movements may produce black, tarry stool or even blood in the stools. There could also be severe or persistent stomach pain associated with Lipoflavonoid use, according to Drugs.com.


