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The best meal-replacement shakes for people with diabetes are nutritious, filling, high in protein and low in carbs.
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Diabetes is one of the most common chronic health conditions in the U.S., affecting more than 30 million Americans, per diabetes statistics. The condition occurs when a person's blood sugar, or glucose, becomes too high for the body to effectively break it down due to a lack of insulin production, says Vandana Sheth, RDN, registered dietitian nutritionist, certified diabetes care specialist and author of My Indian Table.


In order to maintain healthy blood sugar levels, people with diabetes need to eat regularly and consistently, which is one of the reasons meal-replacement shakes have become so popular.

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In addition to providing an on-the-go meal solution, most meal-replacement shakes are relatively low in carbohydrates and high in protein to help manage glucose levels and control overall caloric intake, says Nicole Avena, PhD, assistant professor of neuroscience at Mount Sinai School of Medicine, visiting professor of health psychology at Princeton University and author of What to Eat When You Want to Get Pregnant.

"Carbohydrate tracking is essential for those with diabetes because carbohydrates turn into sugar once digested, which can make it difficult for people to know how to dose their insulin properly," Avena says. "Although homemade meals are always best, meal-replacement shakes are an easy way to get their nutrients in, in a carb-friendly way."

With that in mind, here are the best meal-replacement shakes for people with diabetes.


The Best Meal Replacement Shakes for People With Diabetes

How We Chose

We chatted with registered dietitians and diabetes care specialists to get their expert perspective on the best meal-replacement shakes for people with diabetes and how to find the right product for you. We selected our top picks based on their professional recommendation and criteria including:

  • Quality of ingredients
  • Nutritional value
  • Ability to fill you up
  • Overall caloric content


For more information on how we cover and choose products, click here.


If you have kidney disease or other kidney issues, talk to your doctor before adding meal-replacement shakes to your diet, as the high protein content in some of these shakes may not work for you.

1. Glucerna 30g Protein Shake

Best for Wound Healing

Glucerna Snack Shake

This shake is great for an on-the-go snack.

One common symptom associated with type 2 diabetes is wounds that have trouble healing, per the National Institutes of Health. But a shake with high enough protein can help aid in wound healing, says Laura Cipullo, RD, registered dietitian, certified diabetes care and education specialist and author of Everyday Diabetes Meals for 1 or 2.



This shake is specifically designed for people with diabetes as a way to help manage carbohydrate intake and increase protein intake. "With only 150 calories, this particular shake is perfect for an on-the-go snack, but it should not be used to replace an entire meal," adds Cipullo.

Calories:‌ 150 | ‌Carbohydrates:‌ 7 grams | ‌Protein:‌ 30 grams

Buy it:Amazon.comPrice: ‌$44.72 for a 12-pack

2. 310 Meal Replacement Shake

Best Plant-Based

310 Meal Replacement Shake

This pick is made with nutritious pumpkin, brown rice and pea protein.

Although a bit more pricey, you get a greater value out of the packaging with this shake, which yields 14 individually packed servings that you can mix with water, milk or milk alternatives.


For those seeking a plant-based protein, this is a great option, as it's made from a blend of pumpkin, brown rice protein and pea protein.

"With 15 grams of protein, 5 grams of fiber and 0 grams of added sugar, this shake will provide a fuller feeling than those with less protein and fiber," Roger Adams, PhD, personal trainer, doctor of nutrition and owner of eatrightfitness, tells


Calories:‌ 90 | ‌Carbohydrates:‌ 7 grams | ‌Protein:‌ 15 grams

Buy it:310Nutrition.comPrice: ‌$29.99 for 14 servings

3. Garden of Life Keto Meal

Best for Keto

Garden of Life Keto Meal

The low-carb content of this shake make it great for people following a keto diet.

This doctor-formulated meal-replacement shake is designed for someone following the keto diet, but it can also be quite beneficial for people with diabetes, because going low-carb can help manage blood sugar levels.

Following keto principles, this shake is higher in fat than competitive shakes, which can also be beneficial for people with diabetes. One 2020 study in BMJ Open Diabetes Research & Care found that eating a diet low in carbs and high in fat leads to greater AIC reduction and weight loss.


Calories:‌ 280 | ‌Carbohydrates:‌ 5 grams | ‌Protein:‌ 16 grams

Buy it:Amazon.comPrice: ‌$53.19 for 14 servings

4. Ample Complete Meal Shake

Best Meal Replacement

Ample Complete Meal Shake

This high-calorie shake comes with probiotics to support your gut health.

Ample created this meal-replacement shake with carb control in mind. "It has only 2 grams of sugar and 25 grams of protein, which is designed to slow sugar release into the bloodstream," Avena explains. It is higher in calorie content than others, so it's important to keep that in mind when factoring it into your overall daily amount.


One thing that sets this shake apart from the rest is the fact that it's infused with 40 billion probiotic bacteria from six different strains to help with digestion. A July 2020 study in ‌Scientific Reports‌ showed that probiotics had a beneficial effect on metabolism for people with diabetes.

Calories:‌ 400 | ‌Carbohydrates:‌ 11 grams | ‌Protein:‌ 25 grams

Buy it:AmpleMeal.comPrice: ‌$76.50 for a 12-pack

5. Atkins Protein-Rich Shake

Best Gluten-Free

Atkins Protein-Rich Shake

This shake is gluten-free and full of fiber, to help manage your blood sugar.

The Atkins brand has long been recognized for its commitment to creating replacement shakes and bars that are low in carbohydrates and high in protein.

With just 2 grams of carbohydrates and 15 grams of protein, Avena points out that the macronutrient balance in this shake is ideal. "It also contains 5 grams of fiber for slower digestion and nutritional benefit," she says. "Fiber has been shown to help control blood sugar and cholesterol levels in the blood, which can help prevent diabetic complications."

Calories:‌ 160 | ‌Carbohydrates:‌ 2 grams | ‌Protein:‌ 15 grams

Buy; ‌Price: ‌$17.95 for a 12-pack

6. Splenda Diabetes Care Shake

Best Flavor

Splenda Diabetes Care Shake

Get plenty of protein with this tasty shake.

Pack of 24

Pack of 6

If you're looking for a meal-replacement shake that offers a lot of flavor while giving you the benefit of balanced nutrition, this is a great choice. It has more protein than most shakes for fewer calories, but also has more carbohydrates than most as well.

Still, Sheth notes that the combination of the protein and fats helps manage blood sugar and reduce blood sugar spikes.

Calories:‌ 170 | ‌Carbohydrates:‌ 15 grams | ‌Protein:‌ 16 grams

Buy it:Amazon.comPrice: ‌$39.76 for a 24-pack

7. OWYN Plant-Based Protein Shake

Best for Heart Health

OWYN Plant-Based Protein Shake

A vegan and gluten-free option filled with omega-3s and BCAAs.

In addition to containing a heaping serving of protein (20 grams), this vegan and gluten-free shake also delivers a blend of omega-3-rich ingredients that can provide heart-healthy benefits, notes Sheth.

It also delivers 9 essential amino acids as well as BCAAs (branched chain amino acids) which can be particularly beneficial for muscle recovery.


This rich protein shake is an ideal choice for someone following a vegan or vegetarian diet.

Calories:‌ 180 | ‌Carbohydrates:‌ 10 grams | ‌Protein:‌ 20 grams

Buy it:Amazon.comPrice: ‌$33.29 for a 12-pack

What to Know Before Buying a Meal-Replacement Shake

Before you shop for a meal-replacement shake to help manage your diabetes, here's what nutrition pros want you to know.

1. The Simpler the Ingredients, the Better

Simpler ingredients that are more natural will help with digestion and absorption of nutrients found in nutrient-dense shakes, Avena says. "Meal-replacement shake companies can use fillers and stabilizers to keep their formulas well mixed," she says.

She recommends looking for shakes that have short ingredient lists to keep shopping simple and to reduce unpleasant symptoms.

2. Meal-Replacement Shakes Should Only Be Supplemental

While there are plenty of benefits to these shakes, especially for those with diabetes, they should be a supplemental part of your diet, not the entire diet.

"While it may be OK to have more than one per day to replace a meal, you should still have at least one meal and a snack or two of regular solid foods," Adams says. "This keeps the gastrointestinal system in shape by making it work hard to digest those harder-to-digest solid foods."

3. Daily Value (DV) of Nutrients Matters

"Some meal-replacement products will range from 16 to 20 percent DV of nutrients, and this will provide more sufficient coverage of nutrients if you choose to consume the product rather than eat a meal," says Colleen Johnson, RD, LDN, a registered dietitian nutritionist and adult diabetes educator at Joslin Diabetes Center.

4. Make Sure It Has Fewer Than 45 Grams of Carbs

"Women with type 2 diabetes need about 45 grams of carbohydrate per meal, while men can have about 60 grams of carbohydrate per meal," Cipullo says. "If your meal-replacement shake has 45 grams of carb or less, blood sugar management will be more attainable."

She recommends testing your blood sugar before you drink a given supplement and then two hours after drinking the shake to observe how your blood sugar responds to it.




Is this an emergency? If you are experiencing serious medical symptoms, please see the National Library of Medicine’s list of signs you need emergency medical attention or call 911.