Signs and Symptoms of Enlarged Kidneys

A wide variety of medical conditions can cause enlargment of one or both kidneys. Symptoms are most likely to occur when the enlargement develops quickly, or acutely, such as with a kidney stone or kidney infection. Symptoms may not develop for many years with chronic conditions associated with abnormally large kidneys. Several signs and symptoms might occur with kidney enlargement. These vary depending on the underlying cause.

Signs and Symptoms of Enlarged Kidneys (Image: Nattakorn Maneerat/iStock/GettyImages)


Pain in your abdomen or flank -- the area next to your spine below your ribcage and above your pelvic bones -- occurs with several kidney conditions that might lead to enlargement. The pain may radiate into the groin with some of these ailments. Examples include:

  • Kidney or other urinary tract stone obstructing urine flow into the bladder
  • Kidney infection, or pyelonephritis, which also commonly causes burning pain with urination
  • Blood clot in the main or artery or vein of the kidney
  • Acute interstitial nephritis (AIN) -- inflammation of the kidneys, often caused by a reaction to medication

Urinary Changes

Changes in the urinary frequency, the volume of urine produced and/or appearance of your urine might signal a kidney condition associated with enlargement of the organs. For example, blood in the urine commonly occurs with a kidney infection, urinary tract stone, a blood clot in a major kidney blood vessel and kidney cancer. A decrease or increase in the volume of urine produced can signal failing kidney function, which could be due to AIN or diabetic kidney disease, among others. Increased urinary frequency with a small amount of urine produced could indicate a kidney infection.

Water Retention

Ailments that significantly impair kidney function often lead to water retention. This occurs when the kidneys cannot keep up with demands to filter the blood and maintain water and electrolyte balance in the body. Water retention commonly manifests with one or more signs and symptoms, such as sudden weight gain or swelling of the lower legs, feet or hands, and/or puffiness around the eyes.

Other Signs and Symptoms

A variety of other signs and symptoms can occur with disorders that lead to kidney enlargment. These might include:

  • Fever and chills
  • Nausea and vomiting
  • Loss of appetite
  • Lack of energy
  • Unintended weight loss
  • Abdominal distention
  • Generalized itchiness
  • High blood pressure

Other Considerations, Warnings and Precautions

Because kidney enlargement often causes no symptoms, it is often discovered incidentally on an imaging study such as an an abdominal ultrasound, x-ray or CT scan. Although oversized kidneys often signal a medical problem, this is not always the case. For example, some people are born with only one kidney which grows larger than usual to compensate for lack of a second kidney. Similarly, when one kidney is damaged, the other might enlarge to compensate.

Kidney enlargement must be investigated to determine the underlying cause. Often the enlargement is temporary and does not cause permanent organ damage, such as with a kidney infection or urinary stone. If a chronic kidney disorder is diagnosed, your doctor will advise you about how best to preserve your kidney function.

Seek urgent medical attention if you experience any warning signs or symptoms, including:

  • Severe or worsening flank or abdominal pain
  • Fever or chills
  • Sudden decrease in urine production or lack of urination

Reviewed and revised by: Tina M. St. John, M.D.

Load Comments

Copyright © 2019 Leaf Group Ltd. Use of this web site constitutes acceptance of the LIVESTRONG.COM Terms of Use , Privacy Policy and Copyright Policy . The material appearing on LIVESTRONG.COM is for educational use only. It should not be used as a substitute for professional medical advice, diagnosis or treatment. LIVESTRONG is a registered trademark of the LIVESTRONG Foundation. The LIVESTRONG Foundation and LIVESTRONG.COM do not endorse any of the products or services that are advertised on the web site. Moreover, we do not select every advertiser or advertisement that appears on the web site-many of the advertisements are served by third party advertising companies.