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A basket of grapes on a wooden table
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Grapes are a small, round fruit that can be eaten raw or used to make juice, wine, jelly, raisins, cooking oil and more. They're low in saturated fat, cholesterol and sodium and provide a good source of vitamin C. The USDA's National Nutrient Database reports that one cup of grapes contains 104 calories, most of which come from sugars. Fructose, a sugar that occurs naturally in grapes, can be a source of digestive discomfort for some people.

Fructose Intolerance

Fructose intolerance is a condition that is often inherited and affects people who lack an enzyme needed to break down fructose, a sugar that occurs naturally in fruit. According to the National Institutes of Health, people with fructose intolerance should avoid fruit or risk damage to their liver or kidneys. Fructose malabsorption is similar to fructose intolerance, but less serious in intensity. If you experience abdominal pain after eating grapes, but can eat other fruits without incident, it's not likely your have a fructose intolerance or malabsorption issue.


Gas, though not a serious condition, can cause an extraordinary amount of abdominal pain. According to the National Digestive Diseases Information Clearinghouse, or NDDIC, everyone gets gas. It's typically eliminated from the body by either the mouth, also known as burping, or through the anus, known as flatulence. Gas develops in the digestive tract normally when food breaks down. The body absorbs the digested food as nutrients and eliminates the portion it can't use. Fructose is one of the most common causes of gas.


It's possible that you have a sensitivity to salicylates, a chemical found in certain fruits. According to the Cleveland Clinic, salicylates occur naturally in all plants and some fruits. The chemical acts as a preservative and protects against rotting, harmful bacteria and fungi. Salicylates are an ingredient used to make pain medications and health and beauty products. Symptoms of salicylate sensitivity include abdominal pain, headaches, congestion, hives, and swelling of the face, hands and/or feet.

Other Digestive Conditions

An estimated 60 million to 70 million Americans suffer from digestive conditions, according to the NDDIC. Some of the most common digestive conditions include irritable bowel syndrome, ulcers and gastrointestinal infections. Irritable bowel syndrome, or IBS, causes cramping, abdominal pain, bloating and gas in the large intestine. Certain fruit can cause or worsen symptoms. You may be more susceptible to a flare-up when eating foods containing fructose.

Treating Stomach Pain

If your pain persists past 24 to 48 hours, you should consult your physician. Taking an antacid could help reduce symptoms of heartburn, indigestion and gas. If your belly feels rigid and is tender to the touch, a possible sign of appendicitis, the Mayo Clinic suggests contacting your doctor immediately.

Is This an Emergency?

To reduce the risk of spreading COVID-19 infections, it is best to call your doctor before leaving the house if you are experiencing a high fever, shortness of breath or another, more serious symptom.
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