What Are the Dangers of Calcium Aspartate Anhydrous?

Calcium aspartate anhydrous is an organic calcium compound based on L-aspartic acid and is a form of calcium supplementation. There is some evidence that calcium aspartate anhydrous has a much higher absorption rate than other calcium supplements -- 92 percent. However, you may experience side effects from taking too much calcium.

A woman is experiencing stomach cramping and pain. (Image: GeorgeRudy/iStock/Getty Images)

Kidney Stones

Too much calcium in your body can lead to kidney stones. Hypercalciuria, too much calcium in your urine, is associated with 90 percent of kidney stone cases. MayoClinic.com explains that calcium in the food you eat does not contribute to kidney stones, but calcium supplementation may. Taking calcium aspartate anhydrous with meals may help lower your risk.

Drug Interaction

Supplementation with calcium aspartate anhydrous may interfere with over-the-counter and prescription drug absorption. Calcium interferes with the absorption of iron and lowers the effectiveness of tetracycline. Talk to your pharmacist or consult your doctor about possible drug interactions.

Stomach Problems

Stomach pain, loss of appetite, nausea and vomiting may all be side effects of too much calcium aspartate anhydrous. Because calcium is more bio-available in calcium aspartate anhydrous than other forms of supplementation, it's important not to take more than 500 mg at any one time.


Calcium aspartate anhydrous may have a binding effect and could also cause flatulence. The constipation from calcium aspartate anhydrous alone is often mild, but other medications or supplements may exacerbate the binding.

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