The Highest-Calorie Meal Replacements

Meal replacements are often thought of for weight loss, but they can also be appropriate for weight gain. High-calorie meal replacements such as shakes and bars can help those who struggle to meet their daily caloric needs or need to gain excess weight to enhance their health.

Resource 2.0

Resource 2.0 is a ready-to-drink nutritional supplement manufactured by Nestle Nutrition. It is calorie- and protein-dense and appropriate for those who need to follow a lactose-free, gluten-free, low-residue or kosher diet. An 8-ounce serving provides 480 calories, 21 grams of fat and 20 grams of protein. It is available without a prescription at numerous pharmacies and retailers.


MED PASS 2.0 is a ready-to-drink supplement produced by Hormel Health Labs. It packs a whopping 480 calories, 19 grams of fat and 20 grams of protein into each 8-ounce serving. Available for purchase online, it can be delivered directly to your home. MED PASS 2.0 comes in wild berry, vanilla, no-sugar-added vanilla and butter pecan. The shakes are gluten-free, lactose-free and kosher.

Mighty Shake

Mighty Shakes are small, 4-ounce frozen supplements produced by Hormel Health Labs that are loaded with nutrients. This small serving size provides 200 calories, 6 grams of protein and 6 grams of fat. The shakes are available online for delivery and come in vanilla, strawberry and chocolate flavors.


BOOST Plus is a ready-to-drink meal-replacement shake also available over the counter in numerous retail stores. An 8-ounce serving provides 360 calories, 14 grams of fat and 14 grams of protein. It is available in chocolate, vanilla and strawberry flavors. BOOST Plus is appropriate for those who are lactose- or gluten-intolerant.

Ensure Plus

Ensure Plus shakes are available in five flavors: dark chocolate, vanilla, milk chocolate, strawberry and butter pecan. They provide 350 calories, 13 grams of protein, 24 essential vitamins and minerals, and 11 grams of fat. Ensure is a gluten-free product available in pharmacies, grocery stores and other retailers and does not require a prescription.

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