Which Is Better Vitamin B6 or B12?

Vitamin and nutrients work synergistically to promote health. Vitamin B-6, or pyridoxine and B-12, or cobalamin, are two equally important B vitamins necessary for proper body function. They are part of eight B vitamins known as B complex that work together to help your body perform a variety of functions.

Vitamin B-6 Function

Vitamin B-6 plays a critical role in helping your body produce neurotransmitters, brain chemicals that transmit signals from one nerve cell to another. Serotonin, dopamine and norepinhephrine are three neurotransmitters responsible for appetite, reward mechanism, libido, sleep-wake cycle and mental health. B-6 along with B-12 and B-9, or folic acid, helps regulate homocysteine levels, an amino acid that when elevated, is associated with cardiovascular disease. Vitamin B-6 is also necessary for the absorption of vitamin B-12.

Vitamin B-12 Function

Vitamin B-12 plays an important role in the production of red blood cells, which carry iron, oxygen and nutrients throughout your body. You also need to produce DNA, and RNA, genetic material. It is required to metabolize protein and fats and needed for healthy hair, skin, eyes, liver and proper nervous system function. B-12 works together with B-6 to help release energy from carbohydrates.

Deficiencies

Vitamin B-6 and B-12 are in protein-rich foods including meat, poultry, fish, dairy, eggs, nuts and seeds. You generally get enough B-6 and B-12 from your diet; however, vegans and vegetarians are at risk of developing a deficiency. Stomach surgery can cause malabsorption, leading to a deficiency. Other causes of deficiency include chronic alcohol consumption and pernicious anemia, an autoimmune disease where your immune system produces antibodies against intrinsic factor, an enzyme that helps absorb B-12.

Clinical Uses

Doctors primarily use vitamin B-12 to treat deficiency in the form of monthly intramuscular injections. According to the University of Maryland Medical Center, B-12 is also for fatigue and as a complimentary treatment for elevated homocysteine levels. Because B-6 plays a role in the production of serotonin, and low serotonin levels are associated with depression, B-6 researchers believe B-6 therapy may help reduce symptoms of depression, says UMMC, but more research is necessary.

REFERENCES & RESOURCES
Load comments
PARTNER & LICENSEE OF THE LIVESTRONG FOUNDATION

Copyright © 2019 Leaf Group Ltd. Use of this web site constitutes acceptance of the LIVESTRONG.COM Terms of Use , Privacy Policy and Copyright Policy . The material appearing on LIVESTRONG.COM is for educational use only. It should not be used as a substitute for professional medical advice, diagnosis or treatment. LIVESTRONG is a registered trademark of the LIVESTRONG Foundation. The LIVESTRONG Foundation and LIVESTRONG.COM do not endorse any of the products or services that are advertised on the web site. Moreover, we do not select every advertiser or advertisement that appears on the web site-many of the advertisements are served by third party advertising companies.