How to Cook Buffalo Fish

Buffalo fish is a type of freshwater fish that is best cooked in the oven. It isn't like buffalo-style chicken wings, served with ranch or blue cheese dressing for dipping. If that's disappointing to you, don't despair. You can still cook buffalo fish and baste the fish in creamy, buffalo-style hot sauce just like you do with chicken wings. Experiment with cooking buffalo fish, basting the fish with different ingredients.

Step 1

Preheat the oven to 350 F.

Step 2

Add the butter, pepper sauce, salt and vinegar to a saucepan to make the buffalo-style hot sauce for basting the fish. Place the pan on the stove and heat on medium-high setting until the butter melts. Remove it from the heat, and set it aside.

Step 3

Place the buffalo fish fillets in a baking dish.

Step 4

Baste the fish with the buffalo-style hot sauce, using a cooking brush. Put it in the oven, and bake it for 25 minutes.

Step 5

Flip the fish fillets about 12 minutes into cooking with a spatula, basting the flipped size of the fish as well.

Step 6

Remove the fish from the oven when the internal temperate reaches 145 F on a meat thermometer. The fish should also flake easily when punctured with a fork.

Things You'll Need

  • 3 lbs. buffalo fish fillets

  • Dash salt and pepper

  • 1/3 cup salted butter

  • 1/4 cup hot pepper sauce

  • 1/4 tsp. salt

  • 1 tbsp. vinegar

  • Medium saucepan

  • Baking dish

  • Cooking brush

  • Meat thermometer


If you do not want buffalo-style hot sauce for basting the fish, simply melt 1/3 cup of butter in the medium-sized saucepan and use it in the same way as the sauce.


If you experience muscle pains, vomiting, dark-brown urine or muscle stiffness after eating buffalo fish, seek medical attention. A condition called Haff disease is associated with a toxin found in buffalo fish. If you have questions about eating fish caught or eaten in your area, contact your state’s natural resources or environment department.

Load Comments

Copyright © 2019 Leaf Group Ltd. Use of this web site constitutes acceptance of the LIVESTRONG.COM Terms of Use , Privacy Policy and Copyright Policy . The material appearing on LIVESTRONG.COM is for educational use only. It should not be used as a substitute for professional medical advice, diagnosis or treatment. LIVESTRONG is a registered trademark of the LIVESTRONG Foundation. The LIVESTRONG Foundation and LIVESTRONG.COM do not endorse any of the products or services that are advertised on the web site. Moreover, we do not select every advertiser or advertisement that appears on the web site-many of the advertisements are served by third party advertising companies.