How to Counteract Stomach Upset From Motrin

Motrin is a brand name for the generic drug ibuprofen, a nonsteroidal anti-inflammatory drug, or NSAID. Motrin primarily is used for relieving pain and reducing inflammation, especially in treating arthritis. Using Motrin and other NSAIDs can raise your risk of gastrointestinal distress as well as your risk of having a heart attack or stroke. Always consult your doctor regarding your medications, even over-the-counter drugs.

Taking ibuprofen with food, especially dairy products, minimizes stomach distress. Credit: Fuse/Fuse/Getty Images

Step 1

Take Motrin with a meal or small snack. Credit: Wavebreakmedia Ltd/Wavebreak Media/Getty Images

Take Motrin with a meal or even a small snack to dilute the impact that the drug has on your stomach lining and reduce the likelihood of having an upset stomach.

Step 2

Take Motrin with milk. Credit: Creatas Images/Creatas/Getty Images

Take Motrin with milk. Milk helps reduce stomach acid and minimizes the risk of stomach irritation. A small glass of milk with your Motrin dose can be especially helpful if you don't have the time or opportunity to eat a meal or snack.

Step 3

Limit your intake of caffeine. Credit: Easy_Company/iStock/Getty Images

Limit your intake of caffeine. Caffeinated beverages such as coffee and soda increase irritability in your stomach. Minimize your intake of caffeine throughout the day and avoid taking Motrin with a caffeinated beverage.

Step 4

Avoid alcohol and aspirin. Credit: yordan Rusev/iStock/Getty Images

Avoid alcohol and aspirin. Both alcohol and aspirin will exacerbate the irritating effects of Motrin in your stomach and increase your risk of both stomach upset and a the risk of heart attack or stroke.


Stop taking ibuprofen and call your doctor if you experience stomach pain, bloody vomit, vomit that looks like coffee grounds, heartburn or a black bowel movement because any of these symptoms may be a sign of a serious and potentially life-threatening condition.

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