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Side Effects of Melatonin in Children

author image Lauren McGregory
Educated at the University of Alabama, Lauren McGregory has been writing since 2000. She currently writes for eHow and LIVESTRONG.COM, as well as several private clients. McGregory holds a Master of Science in nursing and currently works in the intensive care unit at the University of Alabama in Birmingham (UAB) Hospital as a registered nurse.
Side Effects of Melatonin in Children
Your child may experience fatigue. Photo Credit: Darrin Klimek/Photodisc/Getty Images

Melatonin, found both naturally in the body and in synthetic form, regulates the hormones associated with the body's natural circadian rhythm, an internal clock that controls normal sleep patterns. Synthetic melatonin allows users to reprogram the body to a more natural pattern, especially someone who has had his normal sleep cycles disturbed. Children, especially those suffering from autism and attention deficit/hyperactivity disorder (ADHD), can benefit from the use of melatonin. recommends that parents consult their physician before administering melatonin to children and to consider the potential side effects associated with this over-the-counter supplement.

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Fatigue is a symptom that is expected when children take melatonin. The supplement triggers the hormones that control a child's sleep cycle, making the child tired. Manufacturers of melatonin supplements recommend that the medication be administered 30 minutes before bedtime. The Centers for Disease Control and Prevention suggests children should have between 9 and 13 hours of sleep per night to prevent fatigue from settling into daytime activities.


Irritability may be present in children who take melatonin, especially during the first few weeks. The changes made from prior sleep habits to new, controlled patterns can leave a child cranky and easily irritated. This irritability should subside within a few weeks, as the body's circadian rhythm begins to reset.


Younger children who recently have been toilet trained may begin to have bed-wetting episodes when taking melatonin. When a child has experienced sleep deprivation, the natural changes that melatonin brings to the body allows him to rest and sleep in a deeper state. This deeper state of sleep can prevent him from waking when he needs to urinate. Once a child has adjusted to the new sleep cycle and has recaptured lost hours of sleep, bed-wetting should subside.


Children may experience sleepwalking episodes while taking melatonin. There is no research to suggest why this occurs, other than it is related to the deep sleep cycle that occurs with melatonin use. The National Institutes of Health notes that this side effect often will cease after a child stops taking the supplement.


Nightmares, also known as night terrors, occur while a child is in a deep sleep. A child's fears and even past events can manifest into these dreams and cause her to wake up afraid and crying. While the use of melatonin allows her to have a better controlled sleep cycle with longer and deeper sleep periods, the deeper sleep, combined with the extended time in this state, can aid in the development of nightmares.

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