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Generic Alternatives to Nexium

author image Cynthia Bateman
Cynthia Bateman is a student at Southern Illinois University Edwardsville where she is pursuing her Master of Arts in English with an emphasis in composition pedagogy. She has most recently been published in the literary journal, "River Bluff Review." She is also a registered professional nurse.
Generic Alternatives to Nexium
Two proton pump inhibitor medications are available without a prescription.

Nexium is the brand name of the generic drug esomeprazole, and belongs in a class of medications known as proton pump inhibitors. It works by turning off, at the cellular level, the part of the stomach, the proton pump, that produces stomach acid, according to Medline Plus. It is prescribed by doctors to treat frequent heartburn, gastroesophageal reflux disease and stomach ulcers. As of 2010, the generic form of Nexium is not available for purchase in the United States, and patients concerned about Nexium's high cost may want to consider other generic proton pump inhibitors on the market.

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Omeprazole is the generic name of the brand name drug Prilosec. Like Nexium, omeprazole works by turning off the acid-producing mechanism in the stomach, or the proton pump, according to Medline Plus. Omeprazole is available for purchase over-the-counter. lists the average monthly price--as of 2010--of taking omeprazole at $19, compared to $240 for Nexium. Patients should consult with their doctors before switching from a prescription medication to an over-the-counter medication.


Pantoprazole is the generic name of the brand name drug Protonix. Pantoprazole is another proton pump inhibitor, but unlike omeprazole, pantoprazole requires a prescription from a doctor. reports that generic pantoprazole costs about $140 a month.

Prevacid 24

While not available in generic form, Prevacid 24 is another proton pump inhibitor that is available for purchase over-the-counter. According to, the average monthly cost of taking Prevacid 24 is $23. Patients looking for an alternative to Nexium may want to ask their doctors if Prevacid 24 is right for them.

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