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Side Effects of Taking Wellbutrin and Celexa

author image Laura Candelaria
Laura Candelaria is a family nurse practitioner and assistant professor of nursing and nutritional science. Her experience includes neonatal and pediatric intensive-care, women's oncology, gynecology, obstetrics, lactation, nutrition and infertility. She has been published in "Nursing Spectrum," "Newsday" and on various websites.
Side Effects of Taking Wellbutrin and Celexa
A prescription pill bottle with white pills spilling out. Photo Credit: ajt/iStock/Getty Images

Both Wellbutrin and Celexa are medications in a class of drugs known as antidepressants. They are used for the treatment of depression and may also be recommended for the treatment of other types of mental illness and smoking cessation. These medications are available by prescription only and should be taken only by those under the direct care of a physician. Some side effects are associated with both Wellbutrin and Celexa.

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Changes in Behavior and Mood

Some patients taking antidepressant medications such as Wellbutrin or Celexa may experience changes in behavior and mood, which can lead to the development of suicidal thoughts. Patients should be under the close supervision of a physician for the first several months of treatment and following any change in dosage. According to, patients should report any new or worsening symptoms to their doctor, such as mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if they feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive, more depressed, or have thoughts about suicide or hurting themselves. The use of alcohol while taking antidepressants may worsen these effects and should be avoided.

Sexual Dysfunction

Wellbutrin and Celexa may lead to sexual dysfunction in some users. Patients may experience a loss of interest in sex, decreased sex drive, impotence, or difficulty having an orgasm, reports Patients should discuss these side effects with their physician, who may recommend a change in medication or dosage or prescribe a medication intended for the treatment of sexual dysfunction. These side effects may be temporary and lessen over time as the body adjusts to antidepressant treatment.


Insomnia may occur in patients taking Wellbutrin or Celexa. Insomnia is having difficulty falling or remaining asleep throughout the night. Natural remedies to induce sleep can include a warm shower or bath, warm milk and relaxation techniques such as meditation. If insomnia begins to negatively impact one's lifestyle, a doctor may prescribe a nightly sleep aid.

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