Side Effects of Mulberry Zuccarin

blood sugar test
Mulberry Zuccarin is marketed to diabetics. (Image: Anette Romanenko/iStock/Getty Images)

New Nordic manufactures and distributes Mulberry Zuccarin as a dietary supplement to control blood sugar levels. Extracts of mulberry have a longstanding use in Chinese medicine in treating a variety of health conditions. This particular supplement functions by blocking carbohydrate absorption via the compound 1-deoxynojirimycin -- a naturally occurring substance in the mulberry leaf. Few clinical studies have evaluated the safety and efficacy of Mulberry Zuccarin and there have been no reported side effects. However, standard side effects exist for the mulberry extract itself. The U.S. Food and Drug Administration has not evaluated the effects of this supplement. You should always consult your physician prior to taking any herbal supplement.

Low Blood Sugar

If you are a type 2 diabetic, taking Mulberry Zuccarin alongside diabetes medications such as alpha-glucosidase inhibitors, DPP-4 inhibitors and biguanides can cause your blood sugar to dip too low, resulting in hypoglycemia. These medications block the absorption of glucose by preventing the breakdown of starches into sugar. It is exceedingly important for you to consult your doctor prior to taking Mulberry Zuccarin to avoid any possible interactions.

Possible Complications for Breast-Feeding and Pregnant Women

Due to the lack of studies on Mulberry Zuccarin and pregnant or breast-feeding mothers, New Nordic advises expecting and current mothers to avoid taking this herbal supplement. Although no reports of Mulberry Zuccarin complications have been reported for women, fetuses and nursing babies may react to the herb.

Gastrointestinal Disruption

Due to the nature of Mulberry Zuccarin, you may experience gastrointestinal disruption like gas, bloating, vomiting, constipation or diarrhea, especially if you have a gastrointestinal health condition such as stomach ulcers, acid reflux or ulcerative colitis, J.K. Aronson says in “Meyler’s Side Effects of Herbal Medicines.” If vomiting occurs, you should immediately seek medical attention as this can indicate an allergy.

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