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Isatis Root Side Effects

author image Rae Uddin
Rae Uddin has worked as a freelance writer and editor since 2004. She specializes in scientific journalism and medical and technical writing. Her work has appeared in various online publications. Uddin earned her Master of Science in integrated biomedical sciences with an emphasis in molecular and cellular biochemistry from the University of Kentucky College of Medicine.
Isatis Root Side Effects
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Derived from the Isatis tinctoria plant, istatis root is a medicinal supplement that was once primarily used as a source of indigo dye. Historically, both Ayurvedic and Chinese medicine have use isatis root in combination with other herbs to help alleviate common cold symptoms and respiratory problems. Be sure to consult your medical provider before using isatis root supplements.

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Side Effects Unknown

Safety data from research studies examining isatis root are severely limited. Due to this lack of research, the side effects associated with the treatment of isatis root supplements are as yet unknown. If you experience any unusual health issues while taking this supplement, contact your medical provider for further evaluation and care.

Potential Side Effects

Isatis root supplements often contain extract from isatis leaves. When used in combination, these herbs may cause side effects in certain people. Health professionals with the Memorial Sloan-Kettering Cancer Center report that isatis leaf may cause nausea or vomiting. Such stomach-related side effects may also contribute to a temporary loss of appetite. If administered as an intramuscular injection, this supplement may cause bruising at the site of treatment. Seek additional care from your physician if these potential side effects of isatis root and leaf persist or become severe.


Discuss all health problems or concerns you may have with your health care provider before taking supplements that contain isatis root. Avoid taking isatis root if you are breastfeeding or pregnant, as the safety of this supplement during pregnancy is unknown. Additionally, do not take isatis root if you are allergic to aspirin. Improper use of isatis root by aspirin-sensitive people may result in a mild to severe allergic reaction. A study cited by MSKCC also reports that treatment with isatis root should be avoided by feeble patients.

Drug Interactions

Always discuss all medications you are taking with your physician before beginning treatment with a new drug or supplement -- including isatis root. As of January 2011, there are no known drug interactions associated with isatis root supplementation because such interactions have yet to be examined.

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