What Are the Side Effects of Docusate Sodium 100 mg?

Constipation, or difficulty producing bowel movements, can affect up to 28% of the population (See references 1, 2, 4) and reduce quality of life (See reference 4). Colace, which is docusate sodium 100 mg (References 2, 3), is a stool softener which allows water and fats in to the stool to help soften material (Reference 5) and prevent dry, hard stools. Docusate sodium 100 mg is expected to produce a bowel movement within 12 to 72 hours (See Reference 2). Docusate sodium is not a laxative; laxatives stimulate the intestinal walls, contracting muscles to clear the bowels (Reference 5) rather than working directly on the stool.

Common Side Effects

Constipation can cause many problems and the stool softener docusate sodium, 100 mg can help. Unfortunately, there are some side effects to using stool softeners as well. The most frequent side effects are stomach or intestinal cramping and diarrhea (See references 3, 6). Throat irritation also may occur when using liquid forms (Reference 6). More severe side effects that require immediate medical attention include allergic reactions such as skin rash, itching, hives or swelling of the face, lips or tongue (See References 3, 6). Rectal bleeding or failure to produce a bowel movement after using docusate sodium 100 mg (See reference 2, 6) may also be signs of a more serious condition and should be brought to the attention of a doctor (Reference 6).


If you are pregnant or breast feeding consult your healthcare professional before using docusate sodium 100mg (Reference 2). Do not use docusate sodium for more than a week without asking your doctor (Reference 6). Docusate sodium 100 mg is not recommended for use if you are currently taking mineral oil for other purposes, as it increases absorption of the mineral oil and can produce other negative side effects (See References 2, 6, 7)

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