Can Uncontrollable Shaking Be Related to Vitamin B-12 Deficiency or Hypothyroidism?

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Control of your muscles requires the proper function of both your nerves and your muscles. If you are shaking uncontrollably, it is a sign that either your nerves or your muscles are not working properly. Thyroid disease, though not hypothyroidism, can cause tremors, and vitamin B-12 deficiency may also lead to uncontrollable shaking.


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Uncontrollable Shaking

Tremor is a term used to describe any sort of involuntary or uncontrollable shaking. There are three main kinds of tremor. A resting tremor occurs when your muscles are not moving. An intention tremor is marked by the tremor appearing at the end of a voluntary muscle movement. Finally, a postural tremor occurs when you stick the affected leg or arm out to the side and hold it up against gravity.


Tremors and Thyroid

The thyroid gland is responsible for controlling your metabolism, which is the amount of energy that your cells burn. Although an underactive thyroid, also known as hypothyroidism, cannot cause any sort of tremor, one of the symptoms of hyperthyroidism is a tremor. Other signs that an unusually active thyroid is causing your tremor are diarrhea, heat intolerance and increased sweating.


Vitamin B-12

A vitamin B-12 deficiency may also play a role in the development of a tremor. Vitamin B-12 is important for making a protein known as myelin, which covers the nerves in your body. A lack of vitamin B-12 can cause this protective sheath to be broken down. According to Dr. Jeffrey Dach and TrueMedMD, one symptom of a vitamin B-12 deficiency is a tremor. However, uncontrollable shaking is not a common symptom of inadequate vitamin B-12 intake.



A tremor can be due to a number of different health problems, including multiple sclerosis, brain damage, alcohol abuse, certain drugs and liver problems. If you develop a tremor, talk to your doctor to try to determine the underlying problem.