Cough Medicines for Pregnant Women

Experiencing a cough while pregnant can cause physical discomfort and generate concern. When simple measures, like sucking on cough drops or sipping hot tea, fail to suppress a cough, some mothers-to-be seek relief with over-the-counter or prescription cough medicine. The safety of different types of cough medicine for pregnant women varies, depending primarily on the specific drug or drugs in the medication and how far along the pregnancy is. Pregnant women with a cough should consult their healthcare provider about the potential risks and benefits before taking cough medicine and to determine whether they need to be seen for further evaluation of their cough.

The safety of different types of cough medicine for pregnant women varies. (Image: Antonio_Diaz/iStock/Getty Images)


Guaifenesin is an expectorant, meaning it helps loosen airway phlegm so it can be coughed up more easily. It is an ingredient in many over-the-counter cough medicines (Mucinex, Robitussin) and some prescription medications. Guaifenesin is a pregnancy category C drug, meaning animal studies suggest it might be harmful to the developing baby, but the risk hasn't been adequately studied in people. An August 2007 article published in "The Journal of Family Practice" reports that one study showed a weak association between guaifenesin use in pregnancy and nervous system abnormalities and hernias in babies. However, it's unclear whether these abnormalities are caused by taking guaifenesin. To be safe, many doctors recommend that pregnant women avoid taking guaifenesin for the first 12 weeks of pregnancy.


Dextromethorphan is a cough suppressant. A study published in February 2001 in "Chest" reported that among 184 women who took dextromethorphan during their pregnancy, there was no increased risk of birth defects among their babies. Dextromethorphan is a common ingredient in over-the-counter cough medicines (Robitussin DM, DayQuil Cough, Delsym) as well as prescription medications. It is a pregnancy category C medication. Although no human studies suggest fetal risk, the drug caused abnormalities in a study conducted with chick embryos. Because no human studies suggest risk, many doctors are comfortable recommending dextromethorphan for cough at any time during pregnancy.


Well known as a pain reliever, codeine is also a prescription cough suppressant. A study published in December 2011 in the "European Journal of Clinical Pharmacology" found neither birth defects nor infant survival rate were adversely affected among 2,666 mothers who took codeine while pregnant, compared to women who did not take the medicine. Codeine is deemed a pregnancy category C drug for short-term use during most of pregnancy, but it also carries the risks of any narcotic medication. The authors of the "European Journal of Clinical Pharmacology" study urge caution during the latter stages of pregnancy because they found a slightly increased risk of unplanned delivery via cesarean section and heavy bleeding after delivery.

Warnings and Precautions

Even with the relative safety of cough remedies established, it is always advisable for a pregnant woman to consult her doctor before taking any medication, supplement or herb -- new or previously used. This is especially important for women less than 12 weeks or more than 38 weeks pregnant.

It's also important to recognize that something as seemingly harmless as a cough sometimes signals a more serious problem. Contact your doctor if you experience: -- Fever or extreme fatigue. -- Difficulty breathing or shortness of breath. -- Green, yellow or thick phlegm. -- Chest pain. -- Severe sore throat. -- Body aches or headache.

Load comments

Copyright © 2019 Leaf Group Ltd. Use of this web site constitutes acceptance of the LIVESTRONG.COM Terms of Use , Privacy Policy and Copyright Policy . The material appearing on LIVESTRONG.COM is for educational use only. It should not be used as a substitute for professional medical advice, diagnosis or treatment. LIVESTRONG is a registered trademark of the LIVESTRONG Foundation. The LIVESTRONG Foundation and LIVESTRONG.COM do not endorse any of the products or services that are advertised on the web site. Moreover, we do not select every advertiser or advertisement that appears on the web site-many of the advertisements are served by third party advertising companies.