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Cold and Flu Center

Flu Symptoms After a Tetanus Injection

author image Rae Uddin
Rae Uddin has worked as a freelance writer and editor since 2004. She specializes in scientific journalism and medical and technical writing. Her work has appeared in various online publications. Uddin earned her Master of Science in integrated biomedical sciences with an emphasis in molecular and cellular biochemistry from the University of Kentucky College of Medicine.
Flu Symptoms After a Tetanus Injection
Young woman suffering from flu like symptoms Photo Credit: CandyBoxImages/iStock/Getty Images

The tetanus injection, which is more commonly referred to as the DTaP vaccine, is a combination vaccine that protects recipients against diptheria, tetanus and pertussis. This vaccination is typically given as a series of five injections over the course of a child's first 4 to 6 years of life, according to KidsHealth, a children's health information website established by the Nemours Foundation. Older children, adolescents and adults can also receive booster tetanus injections when necessary. Patients administered this vaccine can develop flulike symptoms after receiving a tetanus injection.

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After receiving a tetanus injection, patients can experience flu symptoms of fever. Fever symptoms are typically mild and exceed 100.4 degrees Fahrenheit, report health professionals at the Centers for Disease Control. Patients who develop fever may experience symptoms for 1 to 2 days following receipt of the tetanus injection. Additional flu symptoms associated with fever can include sweating or chills. Patients who develop a fever that exceeds 102 degrees Fahrenheit should seek medical care immediately.


Approximately 30 to 40 percent of adults and adolescents who receive a tetanus injection experience headache symptoms, according to the CDC. Flu symptoms of headache are typically mild and can arise shortly after vaccination. Use of an over-the-counter pain medication, such as acetaminophen, can help mitigate headache symptoms in affected patients.

Fatigue or Tiredness

Tiredness is one of the most frequently reported flulike symptom experienced by patients following treatment with the tetanus vaccine, explain medical experts with the Immunization Action Coalition. Affected patients may have difficulty remaining alert and focused throughout the day. These flu symptoms typically subside within 1 to 2 days following receipt of a tetanus injection.

Stomach Upset

Stomach upset symptoms can arise in up to 25 percent of adolescent patients following administration of a tetanus injection, explains the CDC. These stomach-related flu symptoms include stomach pain, nausea, vomiting or diarrhea. Symptoms of diarrhea can be accompanied by sensations of bloating or pain within the abdomen and may contribute to a decrease in appetite.

Body Aches

Treatment with a tetanus injection can cause flulike body aches in patients, report Immunization Action Coalition health professionals. Body aches can be uncomfortable and may exacerbate fatigue symptoms in affected patients. Certain patients may also develop sore joints, swollen lymph glands or a skin rash after receiving this vaccine, explain CDC medical experts. These flulike symptoms after a tetanus injection typically subside within a few days following the vaccination.

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