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Vitamin B-12 & Nerve Regeneration

author image Chad Bjorklund
Chris Bjorklund has been writing professionally since 2004 and has been primarily featured in peer-reviewed scientific journals such as "Nucleic Acids Research" and "Biochemistry." He has also been anonymously published as a content freelancer for several websites. He completed his doctoral degree in biochemistry at Washington State University in 2006.
Vitamin B-12 & Nerve Regeneration
Salmon dinner Photo Credit: gbh007/iStock/Getty Images

Peripheral neuropathy is damage that occurs to your peripheral nerves, resulting in pain, tingling numbness or a burning sensation. Neuropathy usually begins at the end of your longest nerves, which are in your feet and hands. Nerve damage from neuropathy can be caused by a number of different conditions, including diabetes and vitamin B-12 deficiency.

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Vitamin B-12

Vitamin B-12, also known as cobalamin, is an essential water-soluble vitamin that is important for the proper formation of red blood cells. Vitamin B-12, which is easily obtained from animal-based food sources like fish and meat, is also required for healthy brain and nerve functions. According to The Merck Manuals Online Medical Library, vitamin B-12 deficiencies can lead to peripheral neuropathy, although deficiencies are rare and usually occur in vegans and elderly individuals.

Nerve Damage

According to the Neuropathy Association, there are several types of neuropathy, including diabetic, compressive, hereditary, drug- or alcohol-induced, cancer-related, gastrointestinal-related or nutritionally related neuropathies. Most approaches to peripheral neuropathy are targeted at limiting the damage and managing the symptoms. The first line of treatment for any type of neuropathy is to treat the underlying cause, like controlling your diabetes, abstaining from alcohol or drug use, or treating a nutritional deficiency. Physical therapy may be useful for some cases of neuropathy, especially if it is the result of a physical cause like an accident or compressed nerve. Pain medications may be used to effectively manage painful neuropathy.

Nerve Regeneration

While the treatment for most neuropathies is usually to treat the underlying condition, peripheral nerves can regenerate on their own. If the nerves are only damaged, the tingling, burning, numbness or painful sensations may go away once the condition is properly treated and enough time has elapsed to allow the slow growth of the nerve. However, there are some purported nerve regeneration effects stimulated by using methylcobalamin, the activated form of vitamin B-12. In one scientific study published in the April 1994 issue of “Journal of the Neurological Sciences,” researchers found that extremely high doses of methylcobalamin stimulated nerve regeneration in impaired rats. While this report appears promising, it is worth pointing out that virtually no scientific evidence has been published since to further support their findings.

Complications and Warnings

If the underlying causes of peripheral neuropathy are not addressed, the damage to the nerves will keep progressing. Major complications of severe neuropathy include infections that lead to limb loss, permanent limb damage, muscle atrophy, difficulty breathing and swallowing, heart arrhythmias, and complete loss of sensation or movement. Always be wary about the purported benefits of using alternative medicines to treat a serious medical condition, and discuss your intentions with your doctor to beginning any such regimen.

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