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Zinc & Liver Function

author image Shamala Pulugurtha
A freelance writer and blogger since 2007, Shamala Pulugurtha's work has appeared in magazines such as the "Guide to Health and Healing" and prominent websites like Brain Blogger and NAMI California. Pulugurtha has a postgraduate degree in medical microbiology from Manipal Academy of Higher Education, India and has completed course work in psychology and health education.
Zinc & Liver Function
Close-up of a screen during an MRI scan of a patient's liver. Photo Credit: windcatcher/iStock/Getty Images

The liver is the largest organ in the body. It plays a vital role in the digestion of food and removal of toxins, poisons and other harmful substances from the body. Liver diseases include a wide range of problems, such as cirrhosis, hepatitis and jaundice, that affect the proper functioning of the organ. Avoiding alcohol and drugs, using medications wisely and getting vaccinated against hepatitis viruses, along with healthy diet and exercise, can help prevent liver problems. Certain nutrients, such as zinc, are also essential for healthy liver function.

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What is Zinc?

Zinc is an essential trace mineral that plays an important role in growth and development, and in the proper functioning of the immune, nervous and reproductive systems. The Linus Pauling Institute recommends taking about 2 to 12 milligrams of zinc per day, depending on the age and condition of the individual. Meats, dairy products, nuts and beans are dietary sources of zinc. Oral and nasal zinc supplements may also be used to treat zinc deficiency.

Link Between Zinc and Liver Diseases

Zinc deficiency is often linked to liver cirrhosis. In fact, zinc supplementation improves the neurological symptoms and malnutrition associated with liver diseases, say the authors of a study published in the September 2004 edition of the journal “Medical Hypotheses.” Another study in the July 2007 issue of the journal “Digestive Diseases and Sciences” also states that zinc supplementation may help protect against acute and chronic liver diseases. Even alcoholic liver diseases may occur due to decreased levels of zinc in the body, and zinc supplementation may help manage alcoholic liver diseases by inhibiting the formation of free oxygen radicals and enhancing the activity of antioxidant pathways, according to an article in the June 2005 issue of “The American Journal of Pathology.” Some animal studies, such as the one published in the November 2010 issue of the journal “Clinical and Experimental Metabolism,” have demonstrated the antioxidant activity of zinc in animal models and indicated that zinc may prevent oxidative liver damage.

Side Effects

Use of zinc supplements in moderation is generally considered safe. However, mild side effects such as nausea, vomiting and gastric disturbances may sometimes occur. Prolonged use of the supplements can lead to the deficiency of another trace mineral called copper. Intranasal zinc supplements can also lead to loss of sense. The supplements may also interfere with certain antibiotics, such as tetracyclines and quinolones, as well as with anti-convulsant drugs.


Zinc supplements are available at your local pharmacy without a prescription. However, talk to a doctor before using zinc supplements to treat liver conditions to determine if they are right for you. Tell your doctor about any medications you might be taking.

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